This post will not cover why you should use virtualenv/virtualenvwrapper for working on Python projects. For that, you can find an excellent presentation here: http://mathematism.com/2009/07/30/presentation-pip-and-virtualenv/
Checking if pip is installed
Make sure you have pip installed. You can check if you have it installed by typing pip into your terminal:

checking if pip is installed
If you don’t have pip installed but you do have easy_install, you can install pip this way:
Via easy_install:
$ sudo easy_install pip
Other methods of installation for pip can be found at: http://www.pip-installer.org/en/latest/installing.html
Installing virtualenv and virtualenvwrapper
On Ubuntu machines, you might need to run the following before you can install virtualenv and virtualenvwrapper properly:
$ sudo apt-get install python-setuptools python-dev build-essential
I was able to install it on my Mac without any issues (although I already have XCode installed).
To install virtualenv and virtualenvwrapper:
$ pip install virtualenv $ pip install virtualenvwrapper ... $ export WORKON_HOME=~/Envs $ mkdir -p $WORKON_HOME $ source /usr/local/bin/virtualenvwrapper.sh $ mkvirtualenv env1 Installing distribute.......................................... .................................................... .................................................... ...............................done. virtualenvwrapper.user_scripts Creating /Users/derekkwok/Envs/env1/bin/predeactivate virtualenvwrapper.user_scripts Creating /Users/derekkwok/Envs/env1/bin/postdeactivate virtualenvwrapper.user_scripts Creating /Users/derekkwok/Envs/env1/bin/preactivate virtualenvwrapper.user_scripts Creating /Users/derekkwok/Envs/env1/bin/postactivate New python executable in env1/bin/python (env1)$ ls $WORKON_HOME
You may also want to add these 3 lines to your shell startup file (.bashrc, .bash_profile, .profile, etc…):
export WORKON_HOME=$HOME/.virtualenvs export PROJECT_HOME=$HOME/Devel source /usr/local/bin/virtualenvwrapper.sh
You can find the full setup documentation of virtualenvwrapper at: http://www.doughellmann.com/docs/virtualenvwrapper/
Setting up your Virtual Environment for work with your Python Project
In the example below, we’re working on a Django project. You might consider creating a new virtualenv for your work:
$ mkvirtualenv myvirtualenv (myvirtualenv) $ pip install Django==1.3.1 (myvirtualenv) $ pip install south ... (myvirtualenv) $ python manage.py runserver
When you open up a new terminal window, your virtual environment is automatically activated. To re-activate your virtual environment, you can use the following commands:
$ workon myvirtualenv (myvirtualenv) $
This command will automatically put you into “myvirtualenv” environment.
Leave any questions or comments below!